
When people think about cutting-edge research in biology, it's
usually elements such as DNA or fieldwork in the Amazon rainforest that
come to mind. But did you realise how important mathematical and
computational skills are in today's research labs?
Modelling is a
fundamental skill in all science, and models range in complexity from
simple population modelling to ‘whole earth systems’ models, which
attempt to show the circulation of air and oceans across the entire
planet. Model organisms such as Drosophila and Arabidopsis are
well known as a way of investigating some of the fundamental problems
of biology. In the future, computer modelling is set to become one of
the main methods scientists use to explain their theories and make
predictions; as a result, a working knowledge of modelling and its uses
is essential for research scientists today.
As Professor Eliot
Meyerowitz from the Sainsbury Lab, Cambridge, says, this research is
not just intellectually fascinating: “The answers will not only enhance
our fundamental understanding of
life, they will also have important application to a critical problem
that faces the world today – how to feed and fuel a growing population
with limited resources of land, water and energy.”
This
collection of resources introduces the importance of modelling for
A-level biology students and their teachers, and allows students to get
hands on with online tools used by international researchers.
The resource includes the following (download them from the links on the right).
An Introduction to Modelling in Biology. An article introducing the breadth of modelling in biology
ePlant and Biological Modelling - How and Why? An article introducing one specific online software tool used by biologists in their research, ePlant
Investigating Modelling with ePlant - Teaching Notes. A resource for teachers using ePlant with A-level students. The resource contains two activities: Activity One demonstrates the link between expression of different genes in a plant organ and its function, Activity Two shows how protein function is influenced by its structure.
These resources were developed by Freya Scoates, a plant sciences student on a summer internship with SAPS.
See how researchers are using these tools in their work in this 5 minute video looking at how computer models can help us understand how living organisms grow into the correct shapes.